|
KMID : 0613820190290020164
|
|
Journal of Life Science
2019 Volume.29 No. 2 p.164 ~ p.172
|
|
|
Evaluation of the Useful Bioactivities of Spent Mushroom Substrate of Shiitak
|
|
Sung Hwa-Jung
Pyo Su-Jin
Park Jong-Yi
Sohn Ho-Yong
|
|
|
Abstract
|
|
|
|
In Korea, shiitake mushroom, Lentinula edodes, is cultivated on artificial medium containing oak sawdust and wheat bran. The annual production of spent mushroom substrate (SMS) of shiitake, a byproduct of the mushroom industry, is estimated to reach over 50,000 tons per year. This study aimed to improve the use of SMS as a novel bioresource. Hot water extracts of SMS after the first and third harvest were prepared and their bioactivities evaluated. Hot water extracts of uninoculated medium and shiitake were used as controls. Extracts of SMS showed higher radical scavenging of DPPH anions, ABTS cations, nitrites, and a higher reducing power than those of shiitake or medium extracts. After the first and third harvests at 0.5 mg/disc, SMS extracts showed no antibacterial or antifungal activities against the pathogenic and food-spoilage bacteria and fungi. However, they showed good inhibitory activities against α-glucosidase at 0.5 mg/ml. In addition, SMS extracts had strong anti-coagulation activities via their inhibition of thrombin, prothrombin, and blood coagulation factors without platelet aggregation activity. Our results suggested SMS should no longer be perceived as a useless byproduct but should be understood as a novel bioresource, the extracts of which could be developed as antioxidant, antidiabetic, and antithrombosis agents.
|
|
|
KEYWORD
|
|
|
Anti-oxidation, anti-thrombosis, α-glucosidase, Lentinula edodes, spent mushroom substrate (SMS)
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|